The first semester of Organic Chemistry
  • Having taken two semesters of General Chemistry you should have a firm grasp of the organization of the Periodic Table and how the trends found within help us to understand how and why atoms bond with each other.
  • Organic Chemistry begins with a review of concepts such as electronegativity, hybridization, shape, and valence so students need to be happy with these ideas from the beginning. Much of this is discussed on the Preparation page.
  • Organic 1 then progresses with a more in-depth look and Acid-Base chemistry and how chemical concepts may be applied to predict products and the position of an equilibrium in a reaction. This serves as an introduction to reactivity and mechanism.
  • The rest of Organic 1 is spent building towards Chemical Synthesis by studying ideas such as conformation and stereochemistry, which leads to in-depth study of the reactivity of alcohols, alkyl halides, alkynes and alkanes.
  • Below is a rough guide to the major ideas to be discussed and conquered in Organic Chemistry 1. The links will take you to tutorial videos, websites, or other useful files related to each topic .
Chapter 1 - Shape and Structure
The sp3, sp2, sp hybridization patterns and shapes
Shape

The three main hybridization patterns and shapes found in organic molecules

Chapter 2 - Electron Distributions
Dipoles based on electronegativity differences, & resonance delocalization
resonace

The three main patterns observed in delocalized systems

Chapter 3 - Acids & Bases
Interactions between acids and bases resulting in proton transfer
acids

organic acids and bases, pKa and position of equilibria

Chapters 4 & 5- Conformation & Configuration
Dynamic changes in molecular shape versus set identity through configuration
ConformationConfiguration

conformation versus configuration in Organic molecules

Chapter 6 - Reactivity & Mechanism
Reaction basics with electron pairs in making and breaking bonds
mechanism

How molecules are converted to products through bonds being formed and broken

Chapter 7 - Substitution and Elimination @ sp3 Carbon
Nucleophilic substitution and Elimination pathways
SN

Substitution and Elimination pathways at sp3 hybrid carbon

Chapter 8 - Reactions @sp2 Carbon: Addition to Alkenes
Reactions and Mechanisms on the Reactions page
Addition

Concerted and Stepwise additions to alkenes

Chapter 9 - Reactions @sp Carbon: Addition to Alkynes
Reactions and Mechanisms on the Reactions page
Alkynes

Alkyne additions may be syn/anti and Markovnikov/anti-Markovnikov

Chapter 10 - Radical Reactions: Substitutions and Additions
Reactions and Mechanisms on the Reactions page
Radicals

Substitution and addition pathways via free radical intermediates